Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation
![Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* - Journal of Biological Chemistry Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* - Journal of Biological Chemistry](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/asset/dcc16133-44de-4c78-8440-3c9f26fb3bf6/gr1.jpg)
Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* - Journal of Biological Chemistry
![A, p53-KO HCT116 cells were incubated with aciculatin (5–10 µM) for 48... | Download Scientific Diagram A, p53-KO HCT116 cells were incubated with aciculatin (5–10 µM) for 48... | Download Scientific Diagram](https://www.researchgate.net/profile/Chien-Chih-Chen-11/publication/230716310/figure/fig5/AS:213376165781514@1427884250806/A-p53-KO-HCT116-cells-were-incubated-with-aciculatin-5-10-M-for-48-h-Cell-viability.png)
A, p53-KO HCT116 cells were incubated with aciculatin (5–10 µM) for 48... | Download Scientific Diagram
Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression
![Figures and data in Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3 | eLife Figures and data in Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3 | eLife](https://iiif.elifesciences.org/lax/23244%2Felife-23244-fig1-v2.tif/full/,1500/0/default.jpg)
Figures and data in Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3 | eLife
![PUMA-mediated copanlisib-induced apoptosis. A WT and PUMA-KO HCT116... | Download Scientific Diagram PUMA-mediated copanlisib-induced apoptosis. A WT and PUMA-KO HCT116... | Download Scientific Diagram](https://www.researchgate.net/publication/346537015/figure/fig3/AS:983532683948032@1611503873496/PUMA-mediated-copanlisib-induced-apoptosis-A-WT-and-PUMA-KO-HCT116-cells-were-treated.png)
PUMA-mediated copanlisib-induced apoptosis. A WT and PUMA-KO HCT116... | Download Scientific Diagram
PUMA induction by crizotinib is largely dependent on p53. A, HCT116... | Download Scientific Diagram
![Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* - Journal of Biological Chemistry Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* - Journal of Biological Chemistry](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/9a6714da-b592-4398-98ad-d7ba503826bf/gr5.jpg)
Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells* - Journal of Biological Chemistry
![p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels | PNAS p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels | PNAS](https://www.pnas.org/cms/10.1073/pnas.0401002101/asset/3ed6bb06-a21c-4647-b2a5-401c5a23707e/assets/graphic/zpq0190447860001.jpeg)
p300 regulates p53-dependent apoptosis after DNA damage in colorectal cancer cells by modulation of PUMA/p21 levels | PNAS
![Frontiers | p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells | Oncology Frontiers | p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells | Oncology](https://www.frontiersin.org/files/MyHome%20Article%20Library/454697/454697_Thumb_400.jpg)
Frontiers | p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells | Oncology
![PUMA Dissociates Bax and Bcl-XL to Induce Apoptosis in Colon Cancer Cells* - Journal of Biological Chemistry PUMA Dissociates Bax and Bcl-XL to Induce Apoptosis in Colon Cancer Cells* - Journal of Biological Chemistry](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/c914c36c-1599-4692-998e-7a6a6039a2f6/gr1_lrg.jpg)
PUMA Dissociates Bax and Bcl-XL to Induce Apoptosis in Colon Cancer Cells* - Journal of Biological Chemistry
![PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis | Cell Death & Differentiation PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis | Cell Death & Differentiation](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fcdd.2009.51/MediaObjects/41418_2009_Article_BFcdd200951_Fig1_HTML.jpg)
PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis | Cell Death & Differentiation
![Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth | Oncogene Inhibiting oncogenic signaling by sorafenib activates PUMA via GSK3β and NF-κB to suppress tumor cell growth | Oncogene](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fonc.2011.644/MediaObjects/41388_2012_Article_BFonc2011644_Fig5_HTML.jpg)